Ovarian PRP is a treatment that may improve ovarian function. Here, we share more about Ovarian PRP, its potential benefits, and the process to help you decide if it’s right for you.

About Ovarian PRP

What’s PRP?

PRP, or platelet-rich plasma, is obtained from your own blood. We collect a blood sample and then use centrifugation to obtain the rich platelets.

The rich platelets contain growth factors that supercharge the healing and regeneration process in the area where they are injected or infused. They can also promote the development of new blood vessels, which bring oxygen and nutrients to the targeted area.

PRP has been in use and under study since the 1970s, primarily for regenerative purposes in fields like dermatology, orthopedics, and aesthetic surgery.

If you are planning for Ovarian PRP, consider budgeting $4,400.

What’s Ovarian PRP?

Ovarian PRP involves infusing PRP directly into your ovaries. This procedure is also known as ovarian rejuvenation.

We start by drawing a small amount of blood and then we spin it twice in a special centrifuge to extract the rich platelets. We inject these platelets into your ovaries with the help of ultrasound guidance and sedation anesthesia.

Who’s a good candidate for Ovarian PRP?

• Women with diminished ovarian reserve (DOR) or premature ovarian insufficiency (POI).
• Patients who don’t respond to traditional IVF stimulation medications used in Assisted Reproductive Treatment.
• Women experiencing symptoms of early menopause, such as hot flashes, night sweats, and vaginal dryness, can benefit from Ovarian PRP, as it can help alleviate the severity of these symptoms.

PRP can be used either as a standalone therapeutic tool for women with infertility due to low ovarian reserve or in combination with hormonal treatment. Injecting PRP into the ovaries can offer women a chance to have a baby with their own eggs.

What effect will PRP have on my hormone levels, follicles/eggs, and ovaries?

PRP has been found to improve ovarian function. Some studies indicate that PRP can lead to improvements in FSH, LH, estradiol, and AMH hormone levels as early as 2 weeks after the procedure, with effects lasting up to 3 months.

These hormone levels are crucial for fertility, as they are indicators of available follicles or eggs and play a vital role in achieving a desired pregnancy and healthy childbirth.

For some patients, PRP can activate dormant follicles, potentially increasing the number of follicles and improving the chances of obtaining a healthy egg or eggs for a successful live birth.

There is also inconclusive research suggesting that PRP may stimulate ovarian stem cells to develop into follicles, which can then mature into eggs.

What about risks and complications?

Since PRP is derived from your own blood, the risk of rejection or adverse reactions is minimal to none. PRP therapy is entirely natural, very safe, and FDA cleared. Studies have shown positive outcomes after Ovarian PRP injections, including improved egg quality and quantity.

However, there are rare complications associated with the procedure, such as heavier-than-normal bleeding, severe pain or cramping that doesn’t respond to medication, or a fever over 100.2°F. If you experience any of these, please contact our office at (925) 277-0600.

For more about Ovarian PRP, please read: 

• Dr. Aimee – PRP (Platelet Rich Plasma) Ovarian PRP & Uterine PRP
• PubMed – Intraovarian platelet-rich plasma administration could improve blastocyst euploidy rates in women undergoing IVF

Preparing for Ovarian PRP

Select the Appointment Day

Ovarian PRP appointments fill up quickly, as they’re only available two Wednesdays a month. We recommend choosing your date as soon as possible.

• Procedure dates: Ovarian PRP treatments are scheduled for Wednesday morning and early afternoon.

• Location: Dr. Aimee performs Ovarian PRPs at her office in San Ramon, California.

• Check-in and procedure time: On the Monday before your Wednesday appointment, we’ll send you an email with your check-in and procedure time.

Consent Forms

• Sign the Consent Forms: After selecting your appointment date, you’ll receive consent forms to sign, along with an invoice for payment.

Day Before Ovarian PRP

• Stay well-hydrated before your Ovarian PRP. Drink electrolyte-rich drinks like Coconut Water, Gatorade, Watermelon Juice or convenient hydration powder packets from LMNT, DripDrop, or Liquid IV.

• Avoid eating anything after midnight.

Ovarian PRP Day

Before Your Procedure

• You can have clear fluids up to 3 hours before your procedure, limited to water, apple juice, and black coffee. 
• Prescription medications, such as those for blood pressure, can be taken the morning of.

During Your Procedure

• You’ll check in at at Dr. Aimee’s office at 5401 Norris Canyon Road, Suite 104 in San Ramon, CA. Expect to spend approximately 2 hours at from check-in to check-out, with the procedure itself lasting around 30 minutes. 
• After check-in, you’ll complete consent forms for surgery and anesthesia.  
• Your partner or support person can wait in the waiting area. They must stay with you for the remainder of the day after your procedure.

After Ovarian PRP

• Refrain From Activities: After receiving anesthesia, refrain from driving, drinking alcohol, operating machinery, making important decisions, or signing legal documents for at least 24 hours. 

• Nutrition: Begin with small amounts of liquids and progress to a light meal when you feel ready. Avoid spicy, fatty, and heavy foods until you feel ready to advance to your regular nutrition.

• Limit Movement: Rest at home and limit activity the day of the procedure, avoiding strenuous exercise, heavy lifting, or jarring activities.

• Pain Management: Light to moderate cramping and light vaginal spotting are normal. Over-the-counter medications like acetaminophen (Tylenol) and ibuprofen (Advil) should help relieve any discomfort. If you have been prescribed Tylenol #3, take as directed if needed, but not in addition to over-the-counter Tylenol.

• Follicle Count: After your procedure, Dr. Aimee will email you the number of follicles she saw in each ovary.

• Contact Us: If you experience heavier-than-normal bleeding, severe pain or cramping not relieved by medications, or a fever over 100.2 F, email Dr. Aimee or call us at (925) 277-0600.

Start hGH Priming

Begin taking hGH twice a week to support your treatment.

Follicle Check Appointment

• Ultrasound and Blood Work: Two weeks after your Ovarian PRP procedure date, you’ll visit Dr. Aimee’s San Ramon office for an ultrasound to check follicles and a blood draw to measure AMH levels.

• Period Start Date: If your period starts before this appointment, email Dr. Aimee with the subject line, “Post-Ovarian PRP: My period started.”

• Next Steps: Based on the procedure results, Dr. Aimee will recommend the next steps in your treatment plan.